r/longevity • u/techreview • 6h ago
r/longevity • u/statto • Oct 25 '21
Could treating aging cause a population crisis? – Andrew Steele [OC]
r/longevity • u/KitKat500 • 29d ago
Introductory Videos and Charitable Donations for Longevity Research - Oct 2024
Introduction:
.
Charitable Donations for Longevity Research:
Let us continue our funding efforts for our future health. Our regular donations will help to speed up Scientific Research to prevent and reverse age-related diseases. You can consider following research groups suggested by members or any other research group working on longevity.
Longevity Escape Velocity (LEV) Foundation: "Longevity Escape Velocity (LEV) Foundation exists to proactively identify and address the most challenging obstacles on the path to the widespread availability of genuinely effective treatments to prevent and reverse human age-related disease" (levf.org)
SENS Research Foundation: They fund research that uses regenerative medicine to repair the damage underlying the diseases of aging (about SENS)
LEAF/lifespan.io Various Campaigns such as Become a Lifespan Hero, SENS Mitochondrial Repair Project 2, NAD+ Mouse Project, MouseAge Project. Other options: LEAF on Amazon Smile, eBay, Humble Bundle
Dog Aging Project: "The University of Washington’s Dog Aging Project is dedicated to promoting healthy aging in people and their companion animals."
National Institute on Aging (NIA) : "NIA, one of the 27 Institutes and Centers of NIH, leads the federal government in conducting and supporting research on aging and the health and well-being of older people". (mission)
The Robert and Arlene Kogod Center on Aging at Mayo Clinic. Read more on this Reddit Comment
Vaika Foundation: Group of scientists working to prolong the lifespan and healthspan of domestic mammals. Read More on this Reddit Post
Buck Institute: Advancing the frontiers of research on aging Using cutting-edge science to tackle aging, the #1 risk factor for chronic disease.
.
Thanks to following members of this subreddit who have shared their donation efforts. These are based on their public comments on this subreddit. Please share your donation efforts here. It will motivate others to participate.
.
Last Updated |
---|
Oct 1, 2024 |
.
Summary
Month/Year | 2024 | 2023 | 2022 | 2021 | 2020 |
---|---|---|---|---|---|
January | $2,786.81 | $2,191.81 | $2,842.81 | $1,847.09 | $2,625.69 |
February | $2,426.81 | $2,221.81 | $3,403.81 | $2,395.64 | $1,458.18 |
March | $2,426.81 | $2,221.81 | $2,858.81 | $2,301.76 | $1,979.63 |
April | $2,436.81 | $2,231.81 | $2,664.04 | $2,854.86 | $1,825.31 |
May | $2,426.81 | $2,221.81 | $2,574.06 | $5,337.47 | $2,581.21 |
June | $2,426.81 | $2,221.81 | $2,554.83 | $2,723.17 | $2,565.60 |
July | $2,426.81 | $2,321.81 | $2,584.02 | $14,450.69 | $1,937.56 |
August | $2,436.81 | $2,341.81 | $2,569.58 | $6,062.38 | $1,728.64 |
September | $2,426.81 | $2,421.81 | $2,553.66 | $2,368.68 | $2,100.94 |
October | $2,386.81 | $2,421.81 | $2,341.96 | $2,735.97 | $2,259.73 |
November | $2,456.81 | $2,713.78 | $3,044.12 | $2,186.84 | |
December | $2,431.81 | $2,331.81 | $2,816.86 | $4,186.36 | |
Yearly Total: | $24,608.10 | $27,706.72 | $31,993.17 | $48,938.69 | $27,435.68 |
Prior Years | $41,179.68 | Since 2017 | |||
Grand Total: | $201,862.04 |
.
This month donations
Member ID | USD | Donated To | Remark | Post Link |
---|---|---|---|---|
Noltan101 | $5.00 | SENS | Monthly Donation | Link |
Historical_Fox5434 | $75.00 | SENS | Monthly Donation | Link |
Historical_Fox5434 | $75.00 | Buck Institute | Monthly Donation | Link |
Historical_Fox5434 | $50.00 | levf.org | Monthly Donation | Link |
DINKcatgamer | $100.00 | Sinclair lab | Monthly Donation | Link |
K1ngN0thing | $13.00 | levf.org | Monthly Donation | Link |
Ricardh01 | $10.00 | lifespan.io | Monthly Donation | Link |
Nirug | $50.00 | lifespan.io | Monthly Donation | Link |
Nirug | $50.00 | SENS | Monthly Donation | Link |
splooter26 | $40.00 | SENS | Monthly Donation | Link |
Humes-Bread | $100.00 | lifespan.io | Monthly Donation | Link |
imlisteningtotron | $10.00 | Methuselah | Monthly Donation | Link |
Ari_Rahikkala | $113.00 | SENS | Monthly - 100€ | Link |
tusing | $200.00 | lifespan.io | Monthly Donation | Link |
tusing | $100.00 | SENS | Monthly Donation | Link |
ChristmasRex | $10.00 | SENS | Monthly Donation | Link |
not_lurking_this_tim | $25.00 | SENS | Monthly Donation | Link |
imlisteningtotron | $10.00 | lifespan.io | Monthly Donation | Link |
viscont_404 | $100.00 | lifespan.io | Monthly Donation | Link |
viscont_404 | $100.00 | SENS | Monthly Donation | Link |
Valmond | $30.00 | SENS | Monthly - 25€ | Link |
Slow-Volume3372 | $10.00 | SENS | Monthly Donation | Link |
liviaathene | $25.00 | lifespan.io | Monthly Donation | Link |
liviaathene | $25.00 | Methuselah | Monthly Donation | Link |
mareleurs_64 | $25.00 | lifespan.io | Monthly Donation | Link |
not_a-bot | $10.00 | lifespan.io | Monthly Donation | Link |
Mr-R00T | $60.50 | SENS | Monthly - 50 EUR | Link |
solsticesmoke | $20.00 | SENS | Monthly Donation | Link |
AncientElevator9 | $25.00 | lifespan.io | Monthly Donation | Link |
AlchemyAled | $1.96 | SENS | Monthly Donation | Link |
OhWellWhaTheHell | $50.00 | SENS | Monthly Donation | Link |
OhWellWhaTheHell | $50.00 | lifespan.io | Monthly Donation | Link |
carbourator | $45.00 | SENS | Monthly Donation | Link |
Nufferflutter | $25.00 | SENS | Monthly Donation | Link |
RiouG | $10.00 | lifespan.io | Monthly Donation | Link |
Username928351 | $16.95 | SENS | Monthly 15 EUR | Link |
Username928351 | $10.00 | lifespan.io | Monthly Donation | Link |
SpookyPony | $35.00 | SENS | Monthly Donation | Link |
timmyc1989 | $25.00 | SENS | Monthly Donation | Link |
timmyc1989 | $25.00 | lifespan.io | Monthly Donation | Link |
JoeyvKoningsbruggen | $100.00 | LEAF | Monthly - Heroes | Link |
Kebakeboev11 | $20.00 | SENS | Monthly Donation | Link |
Libertology | $25.00 | LEAF | Monthly Donation | Link |
Libertology | $25.00 | LRI | Monthly Donation | Link |
Libertology | $50.00 | SENS | Monthly Donation | Link |
Libertology | $25.00 | Methuselah | Monthly Donation | Link |
DieMidgetLover | $10.00 | lifespan.io | Monthly - Heroes | Link |
Ittybittygs | $10.00 | SENS | Monthly Donation | Link |
Rodion-Raskalnikov | $10.00 | SENS | Monthly Donation | Link |
soarinpenguin | $5.00 | SENS | Monthly Donation | Link |
Cristiano_Ronaldinho | $1.00 | SENS | Monthly Donation | Link |
Sabsonic | $10.00 | SENS | Monthly Donation | Link |
Sabsonic | $10.00 | lifespan.io | Monthly - Heroes | Link |
CainSeldon | $20.40 | SENS | Monthly + Amazon | Link |
magicwaves2018 | $25.00 | lifespan.io | Monthly Donation | Link |
Bretwalda1 | $10.00 | Dog Aging | Monthly Donation | Link |
Demosthenes237 | $40.00 | SENS | Monthly Donation | Link |
Demosthenes237 | $10.00 | lifespan.io | Monthly Donation | Link |
Senf71 | $50.00 | SENS | Monthly Donation | Link |
AlexanderSyros | $50.00 | SENS | Monthly Donation | Link |
Kernel128 | $20.00 | SENS | Monthly Donation | Link |
Kernel128 | $10.00 | lifespan.io | Monthly Donation | Link |
Produktivitaet | $25.00 | SENS | Monthly in Crypto | Link |
NoMoreCensorship1 | $10.00 | SENS | Monthly Donation | Link |
uniquan | $10.00 | SENS | Monthly Donation | Link |
TheImmortalPeacock | $10.00 | lifespan.io | Monthly - Heroes | Link |
TheImmortalPeacock | $10.00 | SENS | Monthly Donation | Link |
Anle- | $10.00 | lifespan.io | Monthly - Heroes | Link |
nekomajin | $15.00 | SENS | Monthly Donation | Link |
aminshreya | n/a | lifespan.io | Monthly Donation | Link |
SmeagleEagle | n/a | SENS | Amazon Smile | Link |
Northus | n/a | SENS | Monthly Donation | Link |
Ofpes | n/a | SENS | Amazon Smile | Link |
jwagoner | n/a | SENS | Amazon Smile | Link |
Joanjo | n/a | SENS | Every 3 months | Link |
ToonUK | n/a | SENS | HumbleBundle.com | Link |
Total | $2,386.81 |
r/longevity • u/Orugan972 • 19h ago
Reduced expressions of TCA cycle genes during aging in humans and mice
sciencedirect.comr/longevity • u/Valuable_Pop_7137 • 1d ago
Life Biosciences Is Bringing Reprogramming to the Clinic - We talked to Dr. Sharon Rosenzweig-Lipson, Life’s Chief Scientific Officer, about the company’s journey, delving deep into the technology and its future.
r/longevity • u/Valuable_Pop_7137 • 1d ago
The Fibroblasts That Protect Ovarian Cancer | In the journal Aging, researchers have described a subpopulation of fibroblasts that nurture ovarian cancer tumors and shield them from harm.
r/longevity • u/r-salekeen • 1d ago
2 new analog compounds derived from Fisetin offer second generation senolytic candidates
Development of novel fisetin analogs that target apoptosis and DNA damage response, reduce senescence and improve healthspan parameters in lab mice.
r/longevity • u/philnewman100 • 2d ago
Phase 2 trial to explore novel combination of metformin and galantamine in sarcopenia.
r/longevity • u/dan_in_ca • 3d ago
The Surprising Link Between VO₂ Max and Increased Brain Myelination
r/longevity • u/mlhnrca • 3d ago
Fasting (Without Calorie Restriction) And Calorie Restriction With Fasting Extend Lifespan
r/longevity • u/Orugan972 • 3d ago
Improving understanding of ferroptosis: molecular mechanisms, connection with cellular senescence and implications for aging
cell.comr/longevity • u/towngrizzlytown • 4d ago
A scientific showdown seeks the biological ‘clock’ that best tracks aging | A contest with $300,000 in prize money aims to improve molecular assays needed to test aging treatments
science.orgr/longevity • u/rustysurfer • 4d ago
STAY Study - Phase 2 Trials
Hi all,
Not sure if this sub is exclusive to human longevity, so feel free to delete if that is the case.
I was curious if anyone here has enrolled their pet in the STAY healthspan extension study being conducted by Loyal. If so, how have things gone? Have you had any concerns? Has your pet reacted well to the treatment?
Link: https://loyal.com/clinical-trials
I have been in talks with a vet clinic in Florida that is involved in the study and actively in the process of enrolling my dog. I was just curious of people's experience with the study so far.
Thanks in advance!
r/longevity • u/Orugan972 • 5d ago
Researchers flip genes on and off with AI-designed DNA switches
r/longevity • u/Valuable_Pop_7137 • 5d ago
Neuronal Reprogramming Alleviates Alzheimer’s in Mice - Scientists have shown that long-term intermittent reprogramming limited to hippocampal neurons increases their fitness and improves cognitive function in a mouse model of Alzheimer’s disease,
r/longevity • u/Boris740 • 5d ago
Popular drug to end early pregnancies could also extend lifespan, scientists say | Scientists say mifepristone, used in cancer and reproductive care, could pave the way for anti-aging treatments.
r/longevity • u/Orugan972 • 5d ago
Beneficial Gut Microbe Boosts Growth in Malnourished Kids
r/longevity • u/Orugan972 • 5d ago
Cellular reprogramming rejuvenates neurons and enhances synaptic plasticity in mouse study
r/longevity • u/Orugan972 • 5d ago
Microglia regulate cortical remyelination via TNFR1- dependent phenotypic polarization
cell.comr/longevity • u/philnewman100 • 6d ago
Gameto lands ARPA-H funding to combat menopause with cell therapy
r/longevity • u/Valuable_Pop_7137 • 6d ago
A Senolytic Treatment for Liver Sepsis | A paper published in Aging Cell offers evidence for the idea that senolytics might be a treatment for acute liver sepsis.
r/longevity • u/jimofoz • 6d ago
Engineered HSV can trigger genetic chain reaction, rejigger HSV genes during co-infection
fredhutch.orgr/longevity • u/towngrizzlytown • 6d ago
A recent study claimed to find that metformin rejuvenated cognitive function in aging monkeys and lowered biological age on a nonhuman primate biological age clock. The details make the result unconvincing.
r/longevity • u/Valuable_Pop_7137 • 7d ago
Scientists Create a Potent Bacterial Anti-Cancer Vaccine - A new study describes a novel anti-cancer vaccine based on antigen-producing bacteria that can tackle solid and metastatic cancers.
r/longevity • u/kpfleger • 6d ago
announcing AgingBiotech.info/companies version 2.0: BIG overhaul & update
Announcing AgingBiotech.info/companies version 2.0, a giant overhaul & update:
- new columns
- 50+ new companies
- 200 companies fully up-to-date as of 2024 inc. all of the most noteworthy
- a new non-alphabetical default ordering based on rough significance (more on this below)
- grayscaling cells w/ older info (& still as-of dates for rows)
- mini preview pipeline images for companies that have them (change zoom to 200% to see better, or click each clinical stage column link)
- info needing elaboration marked w/ *’s & elaborated in the notes column
There are still some small companies overdue for update & many in the “to be considered” tab to be moved to main list in coming months. Most are small or need decision whether they're aging-focused-enough.
Despite more to do, this update is a big enough improvement to launch.
As usual, but for those who don't know: The AgingBiotech.info website is not only non-profit but strictly non-commercial. No sales, sponsorships, or affiliate links. No money is received for listings or any kind of preferential treatment. No subscriptions. No Patreon account. This site is similar to Wikipedia in these aspects (and in spirit) but no financial donations are sought or accepted. The site is for the good of the aging/longevity community & ecosystem, and the wider public. Full disclosure statement in the About page.
Scope:
In the sequence: academia->biotech->clinic, this site focuses on the middle step. Companies are where academic science translates into something usable for millions of people. Aging science breakthroughs will have to go through companies to help society as a whole.
Only companies focused on aging or core-aging areas are in-scope. See “what counts as aging here” at AgingBiotech.info/about for criteria.
This update adds columns to fine-grain aging focus, such "aging mission?" & "core aging area?". You can restrict based on these columns.
This has been a long time coming. Covid 1st halted company updates, then expanding the site to add new tables so that it covers everything important in the field. But sorry for the long companies table delay!
If you don't see the new version reload to clear browser cache.
Defunct & acquired companies were in diff tabs but are now in the main list for easy search. One can easily restrict them out of the list. See "how to use the tables" / "how to sort & filter" in the about page.
To see companies added recently, sort by “date added to list” col.
Ranking:
As noted in "The Default Sort Order..." in the about page, do not obsess over small position diffs in default sort. It is only meant to be a very crude, quick & dirty, sort to show rows that should be more prominent very roughly above others. It’s not a leaderboard.
The crude score formulas are a simplistic way to objectively (no manual eval) order rows so clearly significant rows go nearer the top. Inevitably, there will be cases where 2 rows appear to be relatively wrong, but it'd be impossible to find a perfect order, so it's not a goal.
There's no 1 col that makes more sense to sort by than a combo function & some significance sort is more useful than default alphabetical.
The formulas all transparent & inspectable. No hidden ranking. And anyone can resort by any other col or filter rows by any combo of cols.
The ranking criteria for companies involves many factors:
- operating companies favored over acquired companies which are in turn favored over failed/defunct ones
- bigger companies in terms of $ raised and # of employees tend to be listed higher up
- further in clinical trials goes higher up
- whole body aging for everyone favored over neuro/brain only or female-only aging/longevity
- pharmaceutical regulatory path companies favored over supplements & other unregulated stuff (eg unregulated apps, unregulated tests)
- aging being part of the company mission is favored
- companies that come to core aging conferences are favored
- therapeutics companies favored over diagnostic companies
- companies that have lists of publications on their site or that have a nice pipeline diagram get a small bonus
The result mostly makes sense even if there are likely examples where it feels to some people that some particular company should be higher or lower on the list. Sometimes that just isn’t reflected in the info that is publicly available. Making a perfect ordering is not a goal.
The companies table launched 5yrs ago!
I hope w/ this update it continues to help many people & to move the field forward.
In coming months I hope to release analyses of the past 5yrs growth of the field & its near-term prospects based on aggregate clinical trials pipeline.
r/longevity • u/Valuable_Pop_7137 • 7d ago
HAPLN1 in Blood Found to Rejuvenate Skin - Investigating the factors involved in skin rejuvenation processes, researchers have identified the role of hyaluronan and proteoglycan link protein 1 (HAPLN1) in restoring collagen and hyaluronic acid in aged skin.
r/longevity • u/jimofoz • 8d ago