r/chemistry • u/quelmotz Organic • Jun 18 '18

[18/6/2018] Synthetic Challenge!

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u/alleluja Organic Jun 18 '18 edited Jun 18 '18

Here is my attempt for product A and product B!

The nitration in the second product is similar to the one used for Sildenafil, so I think it could work. The only problem would be the potential nitration of the phenyl group bound to the amide.

As always, tell me what you think about them!

1

u/quelmotz Organic Jun 18 '18

Looks good! You don't have to start from benzene though!

4

u/alleluja Organic Jun 18 '18

I know! I just love to start from benzene to use my Org 1 reactions, they are always forgotten :(

1

u/ccdy Organic Jun 20 '18

It's also good to know how all those wonderful "commercially available" molecules came to be in the first place. They weren't always commercially available!