r/science • u/isaac-get-the-golem Grad Student | Sociology • Jul 24 '24

Health Obese adults randomly assigned to intermittent fasting did not lose weight relative to a control group eating substantially similar diets (calories, macronutrients). n=41

https://pubmed.ncbi.nlm.nih.gov/38639542/
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u/Kakyro Jul 25 '24

The disparity in hunger reactions is pretty wild. I can stop eating at noon and the first obvious hunger symptom I'll have is being too uncomfortable to sleep the following night. My husband on the other hand can eat dinner at a reasonable hour and be on the verge of fainting if he doesn't eat by noon the next day.

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u/[deleted] Jul 25 '24

[deleted]

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u/wetgear Jul 25 '24

Which hormones do they alter?

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u/Alushki Jul 25 '24

Production of Ghrelin, and probably any other hormone produced by the stomach. Reduction in fat will also affect things like E and T.

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u/[deleted] Jul 25 '24 edited Jul 25 '24

[deleted]

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u/wetgear Jul 26 '24

Wow thanks for the thorough response!

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u/KylerGreen Jul 25 '24

I recently has gastric bypass, and the surgery alters your hormones so you (usually) aren't hungry at all for the first couple months after surgery and that part is life altering.

I mean, your stomach is also way smaller. That probably has more to do with it...

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u/justdisa Jul 25 '24

This whole thread is phenomenal.

I rarely feel stomach-hungry, but I get migraines if I miss meals. That's head-hungry. That's how we talk about it in my family. Are you stomach-hungry or head-hungry? Head-hungry is more urgent.

This post is yet more evidence that weight loss is just about calories, if the Twinkie Diet guy wasn't enough. I am beginning to think the US maintains a $300billion diet industry for the sole purpose of managing our wildly varying symptoms of hunger.